October AMP_Digital

A D V A N C E D M A T E R I A L S & P R O C E S S E S | O C T O B E R 2 0 1 8 3 3 debris is one of themajor factors known to reduce the performance and longev- ity of contemporary joint replacement implants. The ideal bearing material has yet to be found and there is signif- icant interest in developing alternative and improved materials. With advanc- es in modern technology, it is antici- pated that multiple approaches may be required to improve the wear and mechanical properties of the polymers currently used as implant bearing ma- terials. Translation of these novel mate- rials and coatings into clinical practice could reduce the associated risks and significantly improve orthopedic im- plant fixation and longevity, leading to better patient outcomes. ~AM&P For more information: Sudipta Seal, professor, Materials Science and Engi- neering, Suite 207, University of Central Florida, Orlando, FL, 32816, 407.823. 5277, sudipta.seal@ucf.edu. Melanie Coathup, UCF Prosthet- ics Cluster Lead, Prof. College of Med- icine, Kaitlyn Crawford and Elizabeth Brisbois, professor, Mat. Sci. Eng. & Prosthetics Cluster, Dr. Sushant Singh, AMPAC and Mat. Sci. Eng. References 1. E. Piskin, Biodegradable Polymers as Biomaterials, J. Biomater Sci. Polym. Ed., 6(9), p 775-95, 1995. 2. A. McKeown, et al., Biomechanical Com- parison of Expanded Polytetrafluoroethy- lene (EPTFE) and PTFE Interpositional Patches and Direct Tendon-to- Bone Repair for Mas- sive Rotator Cuff Tears in an Ovine Model, Shoulder Elbow, 8(1), p 22-31, 2016. 3. X. Zhang, et al., Biodegradable Poly- mers for Orthopedic Applications, J. Macro- molecular Sci., Part C, 33(1), p 81-102, 1993. 4. C.L. Brockett, et al., PEEK and CFR- PEEK as Alternative Bearing Materials to UHMWPE in a Fixed Bearing Total Knee Replacement: An Experimental Wear Study, Wear, 374-375, p 86-91, 2017. 5. Y. Takahashi, et al., Highly Cross- Linked Polyethylene in Total Hip and Knee Replacement: Spatial Distribution of Molecular Orientation and Shape Recovery Behavior, BioMed Res. Intl. 2014, p 13. 6. M. Navarro, et al., Biomaterials in Orthopaedics, J. R. Soc. Interface, 5(27), p 1137-58, 2008. 7. S.M. Kurtz, H.A. Gawel, and J.D. Patel, History and Systematic Review of Wear and Osteolysis Outcomes for First-Generation Highly Cross-Linked Polyethylene, Clin. Orthop. Relat. Res., 469(8), p 2262-77, 2011. 8. S.B. Goodman, et al., Effects of Orthopaedic Wear Particles on Osteo- progenitor Cells, Biomaterials, 27(36), p 6096-101, 2006. 9. X. Shi, et al., Surface Characteri- zation for Ultrahigh Molecular Weight Polyethylene/Hydroxyapatite Gradient Composites Prepared by the Gelation/ Crystallization Method, ACS Applied Matls. & Interfaces, 5(5), p 1768-1780, 2013. 10. S. Kanagaraj, et al., Tribological Characterisation of Carbon Nanotubes/ Ultrahigh Molecular Weight Polyethy- lene Composites: The Effect of Sliding Distance, Intl. J. Surf. Sci. Engrg., 4, p 305-321, 2010. 11. D. Lahiri, et al., Nanotribological Behavior of Graphene Nanoplatelet Reinforced Ultra High Molecular Weight Polyethylene Composites, Tribol. Intl., 70, p 165-169, 2014. 12. J. Baena, J. Wu, and Z. Peng, Wear Performance of UHMWPE and Rein- forced UHMWPE Composites in Ar- throplasty Applications: A Review, Lubricants, 3(2), p 413, 2015. 13. C. Guomei, et al., Biotribological Behaviour of Vitamin E-Blended Highly Cross-Linked UHMWPE in a Hip Joint Simulator, Ind. Lubri. and Tribol., 68(5), p 548-553, 2016. 14. K. Plumlee and C.J. Schwartz, Improved Wear Resistance of Ortho- paedic UHMWPE by Reinforcement with Zirconium Particles, Wear, 267(5), p 710-717, 2009. 15. D.K. Boampong, S.M. Green, and A. Unsworth, N+ Ion Implantation of Ti6Al4V alloy and UHMWPE for Total Joint Replacement Application, J. Appl. Biomater. Biomech., 1(3), p (2003) 164-71, 2003. 16. D. Firouzi, et al., A NewTechnique to Improve the Mechanical and Biological Performance of Ultra High Molecular Weight Polyethylene Using a Nylon Coating, J. Mech. Behav. Biomed. Mater., 32, p 198-209, 2014. 17. V.S. Calderon, et al., Biotribologi- cal Behavior of Ag-ZrCxN1-x Coatings Against UHMWPE for Joint Prostheses Devices, J. Mech. Behav. Biomed. Mater., 41, p 83-91, 2015. 18. V.J. Suhardi, et al., A Fully Func- tional Drug-Eluting Joint Implant, Nature Biomed. Engrg., 1, p 0080, 2017. 19. M. Gao, L. Dai, and G.G. Wallace, Biosensors Based on Aligned Carbon Nanotubes Coated with Inherently Conducting Polymers, Electroanalysis, 15(13), p 1089-1094, 2003. 20. A.G. Ashbaugh, et al., Polymeric Nanofiber Coating with Tunable Com- binatorial Antibiotic Delivery Prevents Biofilm-Associated Infection In Vivo, Proc. Natl. Acad. Sci. USA, 2016. Fig. 3 — Major factors to consider for improving biocompatibility of orthopedic implants and reducing complications.